Molecular Genotyping of Mycobacterium tuberculosis in Mie Prefecture, Japan, Using Variable Numbers of Tandem Repeats Analysis
نویسندگان
چکیده
منابع مشابه
Molecular genotyping of Mycobacterium tuberculosis in Mie Prefecture, Japan, using variable numbers of tandem repeats analysis.
The variable numbers of tandem repeats (VNTR) analysis is a method frequently employed as a molecular epidemiological tool for Mycobacterium tuberculosis genetic fingerprinting. In this study, we characterized the population of M. tuberculosis circulating in Mie Prefecture, Japan, and assessed the utility of the proposed JATA12- and 15-VNTR analyses of 158 M. tuberculosis clinical isolates ...
متن کاملImproved molecular epidemiological analysis of Mycobacterium tuberculosis strains using multi-locus variable number of tandem repeats typing.
*Corresponding author: Mailing address: Division of Bacteriology, Chiba Prefectural Institute of Public Health, 666-2 Nitona, Chuo, Chiba, Chiba 260-8715, Japan. Tel: +81-43-266-6723, Fax: +81-43-265-5544, E-mail: [email protected] Tuberculosis is one of the major bacterial diseases in Japan (1). Advances in the molecular epidemiological analysis of this disease have greatly improved t...
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The number of suicides in Japan has increased to over 30,000 per year since 1998. Similarly, the number of suicides has been increasing in Mie Prefecture. In the present study, we examined the incidence and the circumstances of all suicidal cases that were reported to the Mie Prefectural Police Headquarters during the thirteen-year period 1990-2002. In Mie Prefecture, the number of suicides per...
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OBJECTIVE Establish a typing system for Mycobacterium leprae based on polymorphic DNA structures known as short tandem repeats (STR). DESIGN Assess 16 polymorphic STR for sensitivity, specificity and reproducibility in standard assays using reference strains of M. leprae. RESULTS Primers for 16 STR loci were selected based on PCR product size and for their ability to sequence each STR locus...
متن کاملPolymorphism of variable-number tandem repeats at multiple loci in Mycobacterium tuberculosis.
Genotyping based on variable-number tandem repeats (VNTR) is currently a very promising tool for studying the molecular epidemiology and phylogeny of Mycobacterium tuberculosis. Here we investigate the polymorphisms of 48 loci of direct or tandem repeats in M. tuberculosis previously identified by our group. Thirty-nine loci, including nine novel ones, were polymorphic. Ten VNTR loci had high a...
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ژورنال
عنوان ژورنال: Japanese Journal of Infectious Diseases
سال: 2012
ISSN: 1344-6304
DOI: 10.7883/yoken.65.341